Magnesium Glycinate vs Bisglycinate vs Citrate vs Complex: Which Magnesium Supplement Form to Choose

Two bottles of Balincer Magnesium Bisglycinate 120 capsules with white capsules beside them

Magnesium supplements differ mainly in the form of magnesium they use. Glycinate and bisglycinate (magnesium bound to the amino acid glycine) are known for being gentle on the stomach. Citrate is well absorbed but more likely to loosen stools. Malate is often chosen for daytime use. "Complex" products combine several forms. When comparing, look at the elemental magnesium per serving, not the total compound weight, and stay within the adult upper limit for supplemental magnesium (350 mg a day) unless your doctor advises otherwise.

Magnesium forms compared

Form What it is Known for
Glycinate / bisglycinate Magnesium chelated (bound) to glycine Gentle on digestion; a popular evening choice
Citrate Magnesium bound to citric acid Well absorbed; can have a laxative effect at higher doses
Malate Magnesium bound to malic acid Often chosen for daytime use
Oxide / carbonate Inexpensive, high magnesium content by weight Lower absorption; more digestive upset for some
Complex A blend of several forms Spreads the benefits and trade-offs of each form

Elemental vs compound weight

A label may say "1000 mg magnesium complex," but that is the weight of the whole compound. The amount of actual magnesium, called elemental magnesium, is much lower. Always compare elemental magnesium per serving. For adults, the U.S. National Institutes of Health sets the upper limit for magnesium from supplements at 350 mg a day; food magnesium does not count toward that limit.

Our magnesium supplements

Product Form Label details
Balincer Magnesium Bisglycinate Bisglycinate (chelated) Vegan capsule, no binders or fillers; 30, 60 or 120 capsules; made in the USA, third-party batch tested
Pslalae Magnesium Complex Glycinate, citrate, malate, aspartate, gluconate 150 mg elemental magnesium per capsule (about 36% DV); 30, 60 or 120 capsules; tested by Neptune Labs
TOPLUX Magnesium Complex 1000mg Glycinate, citrate, malate, carbonate 1000 mg compound per 2-capsule serving; 90 veggie capsules (45 days)
Daitea Magnesium Glycinate + Zinc Glycinate plus zinc sulfate and vitamin D3 Vegetable cellulose capsule; made in the USA
Xemenry Magnesium Glycinate Gummies Glycinate gummy with calcium, potassium, D3, B6 and glycine Berry flavor, 2 gummies per serving; 30, 60 or 100 count

Browse all supplements.

How to choose

  • Sensitive stomach: glycinate or bisglycinate.
  • Want several forms in one: a complex.
  • Prefer not to swallow capsules: gummies, but check the sugar and the other added nutrients.
  • Already take a multivitamin or zinc: add up totals so you do not double up on zinc or vitamin D.

Getting magnesium from food comes first: leafy greens, nuts, seeds, beans and whole grains are good sources.

How people take magnesium

  • Follow the serving on the label; do not exceed it without medical advice.
  • Many people take glycinate in the evening with food.
  • Space magnesium at least 2 hours away from certain antibiotics and thyroid medication, as minerals can affect their absorption. Ask your pharmacist.

Who should check with a doctor first

  • Anyone with kidney disease, because the kidneys clear excess magnesium.
  • People taking antibiotics (tetracyclines, quinolones), bisphosphonates, diuretics or heart medications.
  • Pregnant or breastfeeding women.
  • Children: use only products made for children, and only with a pediatrician's guidance.

Common side effects at higher doses include loose stools, nausea and stomach cramps. Stop and seek advice if they occur.

Frequently asked questions

What is the difference between magnesium glycinate and bisglycinate?

Both are magnesium bound to glycine. "Bisglycinate" specifies two glycine molecules per magnesium; in practice the terms are often used interchangeably.

Which magnesium is gentlest on the stomach?

Glycinate and bisglycinate are generally considered the gentlest.

How much magnesium is too much?

For adults, the upper limit from supplements is 350 mg of elemental magnesium a day unless your doctor advises more.

Can I take magnesium with zinc?

Many products combine them. Check total daily zinc from all sources and ask a pharmacist if unsure.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. This article is general information, not medical advice. Consult your doctor before starting any supplement, especially if you are pregnant, nursing, taking medication or have a medical condition.

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